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Phenytoin hypothermia

Web1. okt 2013 · MEASUREMENTS AND MAIN RESULTS: A sum of 121 total and 114 free phenytoin levels were evaluated retrospectively in 10 hypothermia-treated and nine normothermia-treated children who were... Web1. jún 2001 · Therapeutic hypothermia significantly reduces phenytoin elimination in children with severe traumatic brain injury leading to increased drug levels for an extended period of time after cooling, and simulations showed that the increased risk for drug toxicity extends many days beyond the end of the cooling period. 45 PDF

Phenytoin-induced hypothermia Semantic Scholar

WebThe authors examined the effect of mild therapeutic hypothermia on phenytoin pharmacokinetics in 14 patients with brain damage. Each patient was given phenytoin during and after mild therapeutic hypothermia. Plasma concentrations of total phenytoin, unbound phenytoin, and 5-(p-hydroxyphenyl)-5-pheny … the efficiency of a carnot engine is 0.6 https://mindceptmanagement.com

The effect of therapeutic hypothermia on drug metabolism and …

Web1. dec 2006 · The cardiac depressant actions of phenytoin and hypothermia can be additive. Administration of phenytoin in the presence of hypothermia may lead to an adverse cardiac event in children. As... Web22. jan 2024 · They suggest that phenytoin may produce hypothermia indirectly via induction of hepatic cytochrome P450 enzymes and stimulation of steroid clearance, which could lead to the induction or exacerbation of adrenal insufficiency in certain patients. In the other cases 6 7 no underlying cause such as hypoadrenalism was reported. In all cases ... Web1. nov 2006 · Volume 13, Issue 9, November 2006, Pages 953-955. Case report. Is phenytoin administration safe in a hypothermic child? the efficiency of data assimilation

Effect of Mild Therapeutic Hypothermia on Phenytoin …

Category:Is phenytoin administration safe in a hypothermic child?

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Phenytoin hypothermia

Is phenytoin administration safe in a hypothermic child?

Web19. nov 2024 · An 87-year-old man developed coma and hypothermia during the treatment with phenytoin for epilepsy [ route not stated ]. The man, who had epilepsy and hypovolemia, admitted to the hospital due to COVID-19 and congestive heart failure. He had been receiving phenytoin 300mg controlled release daily for epilepsy. WebTrial-drug vials contained levetiracetam (50 mg per milliliter), fosphenytoin (16.66 mg phenytoin equivalents [mgPE] per milliliter), or valproate (33.33 mg per milliliter).

Phenytoin hypothermia

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WebPhenytoin elimination in a child during hypothermia for ... - BMJ Group. EN. English Deutsch Français Español Português Italiano Român Nederlands Latina Dansk Svenska Norsk Magyar Bahasa Indonesia Türkçe Suomi Latvian Lithuanian česk ... Phenytoin elimination in a child during hypothermia for ... - BMJ Group WebFosphenytoin is metabolized by CYP2C, has a narrow therapeutic range, and is a commonly used antiepileptic medication. The objective of the study was to evaluate the impact of therapeutic hypothermia on phenytoin levels and pharmacokinetics in …

WebMay reduce serum levels with anticonvulsants (e.g. phenytoin, barbiturates, carbamazepine). May enhance the anticoagulant effect of warfarin and other coumarins with prolonged use. ... May cause severe hypothermia with phenothiazine. Contraindications. Paracetamol is contraindicated in patients with severe renal function impairment and hepatic ... Web1. nov 2006 · We emphasize that the cardiac depressant actions of phenytoin and hypothermia may be synergistic. Phenytoin is a commonly used drug in neuroanaesthesia, neurology and neurosurgical practice. Its administration in hypothermic children may have far-reaching cardiac consequences and prevention of hypothermia would be the most …

Web1. júl 2003 · No cause of hypothermia could be identified but as his phenytoin levels normalised, his body temperature also improved. There are three other reported cases of phenytoin- induced... Web1. jan 2024 · No cause of hypothermia could be identified but as his phenytoin levels normalised, his body temperature also improved. There are three other reported cases of phenytoin- induced hypothermia in the literature. Could this be a rare cause of hypothermia? http://dx.doi.org/10.1136/bcr-2024-227443 Request Permissions

Web7. sep 2024 · Hypothermia is a rare, but potentially fatal adverse effect of antipsychotic drug (APD) use. ... Possible long-acting risperidone-induced hypothermia precipitating phenytoin toxicity in an elderly patient. J Clin Pharm Ther (2011) 36:426–42. 10.1111/j.1365-2710.2010.01189.x ...

Web22. jan 2024 · This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our privacy notice and cookie policy. the efficient markets hypothesis koofersWeb1. jún 2011 · We report the first known case of hypothermia possibly associated with long‐acting risperidone depot injection, precipitating further adverse events secondary to supratherapeutic phenytoin concentrations. View on Wiley ncbi.nlm.nih.gov Save to Library Create Alert Cite 14 Citations Citation Type More Filters the efficacy of pheromonal actions depends onWebNo cause of hypothermia could be identified but as his phenytoin levels normalised, his body temperature also improved. There are three other reported cases of phenytoin- induced hypothermia in the literature. the efficacy of a placebo may notWeb22. jan 2024 · Phenytoin-induced hypothermia. A 60-year-old man with cerebral palsy and epilepsy was admitted with acute lethargy and deterioration in coordination. He was noted to be hypothermic at 35°C on admission. Routine work-up revealed toxic levels of phenytoin. the efficacy of hypnotherapy reading answersWebMeasurements and main results: A sum of 121 total and 114 free phenytoin levels were evaluated retrospectively in 10 hypothermia-treated and nine normothermia-treated children who were randomized to 48 hours of cooling to 32-33°C followed by slow rewarming or controlled normothermia. the effing foundation for sex-positivityWeb1. nov 2006 · The cardiac depressant actions of phenytoin and hypothermia can be additive. Administration of phenytoin in the presence of hypothermia may lead to an adverse cardiac event in children. As phenytoin is a commonly used drug, clinicians need to … the efficiency of induction welderWeb23. dec 2010 · Administration of intravenous phenytoin during hypothermia may produce additive cardiac depression such as severe bradycardia and hypotension, and close monitoring is indicated. 103 the efficiency of adapting aspiration levels